Detalhe da pesquisa
1.
Phase 3 Trial of RNAi Therapeutic Givosiran for Acute Intermittent Porphyria.
N Engl J Med
; 382(24): 2289-2301, 2020 06 11.
Artigo
Inglês
| MEDLINE | ID: mdl-32521132
2.
Risk for incident comorbidities, nonhepatic cancer and mortality in acute hepatic porphyria: A matched cohort study in 1244 individuals.
J Inherit Metab Dis
; 46(2): 286-299, 2023 03.
Artigo
Inglês
| MEDLINE | ID: mdl-36546345
3.
Porphyrin precursors and risk of primary liver cancer in acute intermittent porphyria: A case-control study of 188 patients.
J Inherit Metab Dis
; 46(6): 1186-1194, 2023 11.
Artigo
Inglês
| MEDLINE | ID: mdl-37650859
4.
Phase 1 Trial of an RNA Interference Therapy for Acute Intermittent Porphyria.
N Engl J Med
; 380(6): 549-558, 2019 02 07.
Artigo
Inglês
| MEDLINE | ID: mdl-30726693
5.
RNAi therapy with givosiran significantly reduces attack rates in acute intermittent porphyria.
J Intern Med
; 291(5): 593-610, 2022 05.
Artigo
Inglês
| MEDLINE | ID: mdl-35067977
6.
Risk of primary liver cancer in acute hepatic porphyria patients: A matched cohort study of 1244 individuals.
J Intern Med
; 291(6): 824-836, 2022 06.
Artigo
Inglês
| MEDLINE | ID: mdl-35112415
7.
EXPLORE: A Prospective, Multinational, Natural History Study of Patients with Acute Hepatic Porphyria with Recurrent Attacks.
Hepatology
; 71(5): 1546-1558, 2020 05.
Artigo
Inglês
| MEDLINE | ID: mdl-31512765
8.
International Porphyria Molecular Diagnostic Collaborative: an evidence-based database of verified pathogenic and benign variants for the porphyrias.
Genet Med
; 21(11): 2605-2613, 2019 11.
Artigo
Inglês
| MEDLINE | ID: mdl-31073229
9.
Phase I open label liver-directed gene therapy clinical trial for acute intermittent porphyria.
J Hepatol
; 65(4): 776-783, 2016 10.
Artigo
Inglês
| MEDLINE | ID: mdl-27212246
10.
Tackling Health Inequities and Reducing Obesity Prevalence: The EPODE Community-Based Approach.
Ann Nutr Metab
; 68 Suppl 2: 35-8, 2016.
Artigo
Inglês
| MEDLINE | ID: mdl-27300305
11.
The incidence of inherited porphyrias in Europe.
J Inherit Metab Dis
; 36(5): 849-57, 2013 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-23114748
12.
High risk of primary liver cancer in a cohort of 179 patients with Acute Hepatic Porphyria.
J Inherit Metab Dis
; 36(6): 1063-71, 2013 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-23344888
13.
Comment on Ramai et al. Risk of Hepatocellular Carcinoma in Patients with Porphyria: A Systematic Review. Cancers 2022, 14, 2947.
Cancers (Basel)
; 15(3)2023 Jan 28.
Artigo
Inglês
| MEDLINE | ID: mdl-36765753
14.
Liver transplantation for erythropoietic protoporphyria in Europe.
Liver Transpl
; 17(9): 1021-6, 2011 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-21604355
15.
A Drug-Drug Interaction Study Evaluating the Effect of Givosiran, a Small Interfering Ribonucleic Acid, on Cytochrome P450 Activity in the Liver.
Clin Pharmacol Ther
; 110(5): 1250-1260, 2021 11.
Artigo
Inglês
| MEDLINE | ID: mdl-34510420
16.
Combined liver and kidney transplantation in acute intermittent porphyria.
Transpl Int
; 23(6): e18-21, 2010 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-20028496
17.
Challenges in the management of acute intermittent porphyria with recurrent attacks during pregnancy: A case report.
Clin Case Rep
; 8(12): 2483-2487, 2020 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-33363763
18.
Protection from phototoxic injury during surgery and endoscopy in erythropoietic protoporphyria.
Liver Transpl
; 14(9): 1340-6, 2008 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-18756472
19.
Safety, pharmacokinetics and pharmocodynamics of recombinant human porphobilinogen deaminase in healthy subjects and asymptomatic carriers of the acute intermittent porphyria gene who have increased porphyrin precursor excretion.
Clin Pharmacokinet
; 46(4): 335-49, 2007.
Artigo
Inglês
| MEDLINE | ID: mdl-17375984
20.
Vitamin D-binding protein as a biomarker of active disease in acute intermittent porphyria.
J Proteomics
; 127(Pt B): 377-85, 2015 Sep 08.
Artigo
Inglês
| MEDLINE | ID: mdl-25979770